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Recombinant Human Neutrophil gelatinase-associated lipocalin protein(LCN2) (Active)

Recombinant Human Neutrophil gelatinase-associated lipocalin protein(LCN2) (Active)
2.053,00 €
Artikelnummer: CSB-AP000461HU-500

Verfügbarkeit: Lieferzeit auf Anfrage

Kostenlose Lieferung innerhalb Österreichs!
Recombinant Human Neutrophil gelatinase-associated lipocalin protein(LCN2) (Active), Host: E.Coli

Details

Species: Homo sapiens (Human). Function: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation. Subcellular Location: Secreted. Protein Families: Calycin superfamily, Lipocalin family. Tissue Specificity: Expressed in bone marrow and in tissues that are prone to exposure to microorganism. High expression is found in bone marrow as well as in uterus, prostate, salivary gland, stomach, appendix, colon, trachea and lung. Not found in the small intestine or peripheral blood leukocytes. Tag Info: Tag-Free.

Zusatzinformation

Artikelnummer CSB-AP000461HU-500
Hersteller Cusabio
Herstellernummer CSB-AP000461HU-500
Verpackungseinheit 500 µg
Mengeneinheit FL
Reaktivität Keine Herstellerangabe
Klonalität Keine Herstellerangabe
Wirt / Host Escherichia Coli
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage