Tag Info: N-terminal 6xHis-tagged. MW: 19.9 kDa. Function: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). Subcellular Location: Cytoplasm, cytosol, Mitochondrion. Protein Families: Frataxin family. Tissue Specificity: Heart, liver, skeletal muscle, kidney, spleen and thymus. Weakly expressed in the brain and lung.
|Wirt / Host||Escherichia Coli|
|Datenblatt|| Auf Anfrage|
|MSDS|| Auf Anfrage|