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Recombinant Porcine parvovirus Capsid protein VP1,partial

Recombinant Porcine parvovirus Capsid protein VP1,partial
1.320,00 €
Artikelnummer: CSB-MP323858PQB-100

Verfügbarkeit: Lieferzeit auf Anfrage

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Recombinant Porcine parvovirus Capsid protein VP1,partial, Host: Mammalian cell

Details

Organism: Porcine parvovirus (strain NADL-2) (PPV). Function: Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s). VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity). Subcellular Location: Virion, Host nucleus. Protein Families: Parvoviridae capsid protein family. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged

Zusatzinformation

Artikelnummer CSB-MP323858PQB-100
Hersteller Cusabio
Herstellernummer CSB-MP323858PQB-100
Verpackungseinheit 100 µg
Mengeneinheit FL
Reaktivität Keine Herstellerangabe
Klonalität Keine Herstellerangabe
Wirt / Host Mammalian Cell
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage