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Recombinant Rotavirus A Outer capsid protein VP4,partial

Recombinant Rotavirus A Outer capsid protein VP4,partial
308,00 €
Artikelnummer: CSB-EP325504RIV-50

Verfügbarkeit: Lieferzeit auf Anfrage

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Recombinant Rotavirus A Outer capsid protein VP4,partial, Host: E.coli

Details

Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. MW: 33.2 kDa. Function: Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. According to the considered strain, VP4 seems to essentially target sialic acid and/or the integrin heterodimer ITGA2/ITGB1 (By similarity). Subcellular Location: Outer capsid protein VP4: Virion, Host rough endoplasmic reticulum, Note=Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7, these enveloped particles also contain VP4, As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles (By similarity), SUBCELLULAR LOCATION: Outer capsid protein VP8*: Virion, Note=Outer capsid protein, SUBCELLULAR LOCATION: Outer capsid protein VP5*: Virion. Protein Families: Rotavirus VP4 family.

Zusatzinformation

Artikelnummer CSB-EP325504RIV-50
Hersteller Cusabio
Herstellernummer CSB-EP325504RIV-50
Verpackungseinheit 50 µg
Mengeneinheit FL
Reaktivität Keine Herstellerangabe
Klonalität Keine Herstellerangabe
Wirt / Host Escherichia Coli
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage