• Sie sehen derzeit Listenpreise. Um Ihren Vorteilspreis zu sehen, melden Sie sich mit Ihrem Kundenkonto an.

Recombinant Vesicular stomatitis Indiana virus RNA-directed RNA polymerase L(L),partial

Recombinant Vesicular stomatitis Indiana virus RNA-directed RNA polymerase L(L),partial
680,00 €
Artikelnummer: CSB-EP806333VBE-200

Verfügbarkeit: Lieferzeit auf Anfrage

Kostenlose Lieferung innerhalb Österreichs!
Recombinant Vesicular stomatitis Indiana virus RNA-directed RNA polymerase L(L),partial, Host: E.coli

Details

Tag Info: N-terminal 6xHis-tagged. MW: 25.4 kDa. Function: RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3' leader promoter, and transcribes subsequently all viral mRNAs with a decreasing efficiency. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein acts as a processivity factor. Capping is concommitant with initiation of mRNA transcription. Indeed, a GDP polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both acticities being carried by the viral polymerase. Polyadenylation of mRNAs occur by a stuttering mechanism at a slipery stop site present at the end viral genes. After finishing transcription of a mRNA, the polymerase can resume transcription of the downstream gene. Subcellular Location: Virion, Host cytoplasm. Protein Families: Rhabdoviridae protein L family.

Zusatzinformation

Artikelnummer CSB-EP806333VBE-200
Hersteller Cusabio
Herstellernummer CSB-EP806333VBE-200
Verpackungseinheit 200 µg
Mengeneinheit FL
Reaktivität Indiana Vesiculovirus
Klonalität Keine Herstellerangabe
Wirt / Host Escherichia Coli
Methode Keine Herstellerangabe
Isotype Keine Herstellerangabe
Gene ID Nein
Datenblatt Auf Anfrage
MSDS Auf Anfrage