X-VIVO™ 15 Media are similar in composition to X-VIVO™ 10 Media and have been optimized for the proliferation of tumor infiltrating lymphocytes (TIL) under serum-free conditions. X-VIVO™ 15 Media support the proliferation of purified CD3+ cells isolated from peripheral blood and human tumors. X-VIVO™ 15 Media can also be used to support the growth of human monocytes, macrophage cells and cell lines, PBL, granulocytes, and natural killer (NK) cells. In addition, X-VIVO™ 15 Media provide a serum-free environment for the expansion of HUT-78 and related human lymphocytic cell lines. X-VIVO™ 15 is similar in composition to X-VIVO™ 10 and has been optimized for the proliferation of Tumor Infiltrating Lymphocytes (TIL) under serum-free conditions. Please see Supplemental Information for additional hematopoietic cell applications.X-VIVO™ 15, catalog number 04-418 and 02-060 are formulated with L-glutamine, gentamicin, and phenol red. Catalog number 04-744Q and 02-061Q contains L-glutamine but does not contain gentamicin or phenol red. Catalog number BE02-053Q is formulated with L-glutamine, gentamicin, recombinant transferrin, and phenol red. Catalog number BE02-054Q, contains L-glutamine and recombinant transferrin but does not contain gentamicin or phenol red. The recombinant transferrin replaces native transferrin.All BioWhittaker™ Cell Culture Media products are for Research Use Only (RUO) and are not approved for human or veterinary use or for use in clinical or in vitro diagnostic procedures.