Product Description: 13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals.
Formula: C18H32O4
References: [1]Gardner HW, et al. Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism. Biochim Biophys Acta. 1989 Feb 20;1001(3):274-81./[2]Reinaud O, et al. Oxidative metabolism of linoleic acid by human leukocytes. Biochem Biophys Res Commun. 1989 Jun 15;161(2):883-91./[3]Glasgow WC, et al. The linoleic acid metabolite, (13S)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenotypes. J Biol Chem. 1997 Aug 1;272(31):19269-76.
CAS Number: 33964-75-9
Molecular Weight: 312.44
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: EGFR;Endogenous Metabolite
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