Description: 2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.
CAS Number: 168427-74-5
Formula: C13H19N5O5
Molecular Weight: 325,32
References: Marais G, et al. Chemo-enzymatic synthesis of 2'-O-methoxyethyl ribonucleosides using a phosphodiesterase from Serratia marcescens. Appl Microbiol Biotechnol. 2005;66(5):512-519.