Product Description: 2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].
Applications: Cancer-programmed cell death
Formula: C10H13N3O5
References: [1]bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes/[2]Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04.
CAS Number: 206055-69-8
Molecular Weight: 255.23
Compound Purity: 98.59
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Nucleoside Antimetabolite/Analog