Product Description: 3,4-Dihydroxyamphetamine (α-Methyldopamine) (hydrochloride) is a secondary metabolite of 3,4-Methylenedioxymethamphetamine (MDMA). 3, 4-dihydroxyamphetamine (hydrochloride) is cytotoxic to rat hepatocytes. 3, 4-dihydroxyamphetamine (hydrochloride) is also used in the study of high blood pressure[1][2][3].
Formula: C9H14ClNO2
References: [1]Schwaninger AE, et al. Urinary excretion kinetics of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and its phase I and phase II metabolites in humans following controlled MDMA administration. Clin Chem. 2011 Dec;57(12):1748-56. /[2]Carvalho M, et al. Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates. Arch Toxicol. 2004 Jan;78(1):16-24./[3]Waldmeier P, et al. On the role of alpha-methyldopamine in the antihypertensive effect of alpha-methyldopa. Naunyn Schmiedebergs Arch Pharmacol. 1975;289(3):303-14.
CAS Number: 828-06-8
Molecular Weight: 203.67
Research Area: Neurological Disease; Cardiovascular Disease
Target: Drug Metabolite
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