3FAx-Neu5Ac, CAS 117405-58-0

Product Description: 3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C22H30FNO14

References: [1]Cory D Rillahan, et al. Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol. 2012 Jul;8(7):661-8. /[2]Natoni A, et al. Inhibition of Sialylation Impairs Adhesion on Madcam-1 and E-Selectin and Sensitize Multiple Myeloma Cells to Bortezomib in a Xenograft Mouse Model. Blood, 2018, 132: 3204.

CAS Number: 117405-58-0

Molecular Weight: 551.47

Compound Purity: 99.88

Research Area: Metabolic Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Sialyltransferase

• Artikelnummer: MEXHY-110288-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-110288-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK