Application Note: ICC/IF: 10μg/ml. IHC-P: 3.75μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89596-PEP).
Specificity/Sensitivity: This antibody is expected to recognise both the longer membrane-bound form of human ADAM12 (NP_003465.3) and the shorter soluble ADAM12 splice isoform (NP_067673.2). This antibody does not cross-react with other ADAMS.
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014]
Uniprot ID: O43184
Antigen Species: Human
Immunogen: Peptide with sequence AARPLPVSPARALC, from the N Terminus of the protein sequence according to NP_003465.3; NP_067673.2.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: ADAM metallopeptidase domain 12
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