Adriforant (hydrochloride hydrate), CAS 2096455-90-0

Shelf life (days): 1460

Info: A histamine H4 receptor antagonist (Ki = 6.17 nM); prevents histamine-induced shape change, CD11b protein upregulation, and actin polymerization in isolated human eosinophils (IC50s = 0.65, 4.9, and 1.3 nM, respectively); inhibits histamine-induced calcium influx in primary mouse dorsal root ganglion neurons at 10 µM; decreases ear thickness and reduces basophils, eosinophils, neutrophils, and T cell infiltration in a mouse model of calcipotriol-induced atopic dermatitis at 50 mg/kg per day

Formulation: A solid

Formal Name: N⁴-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)-1-pyrrolidinyl]-2,4-pyrimidinediamine, dihydrochloride hydrate

Purity: ≥95%

Formula Markup: C13H22N6 • 2HCl [XH2O]

Formula Weight: 335.3

CAS Number: 2096455-90-0

• Artikelnummer: CAY43638-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 43638-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK