Agmatine (sulfate) (Standard), CAS 2482-00-0

Agmatine (sulfate) (Standard), CAS 2482-00-0
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MEXHY-101238R-0
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Product Description: Agmatine (sulfate) (Standard) is the analytical standard of Agmatine (sulfate). This product is intended for research and analytical applications. Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor.

Formula: C5H16N4O4S

References: [1]Li G, et al. Agmatine: an endogenous clonidine-displacing substance in the brain. Science. 1994 Feb 18;263(5149):966-9./[2]Reis DJ, et al. Is agmatine a novel neurotransmitter in brain? Trends Pharmacol Sci. 2000 May;21(5):187-93./[3]Galea E, et al. Inhibition of mammalian nitric oxide synthases by agmatine, an endogenouspolyamine formed by decarboxylation of arginine. Biochem J. 1996 May 15;316 ( Pt 1):247-9./[4]Morrissey JJ, et al. Agmatine activation of nitric oxide synthase in endothelial cells. Proc Assoc Am Physicians. 1997 Jan;109(1):51-7./[5]Zomkowski AD, et al. Agmatine produces antidepressant-like effects in two models of depression in mice. Neuroreport. 2002 Mar 25;13(4):387-91./[6]Ahn SS, et al. Effects of agmatine on blood-brain barrier stabilization assessed by permeability MRI in a rat model of transient cerebral ischemia. AJNR Am J Neuroradiol. 2015 Feb;36(2):283-8./[7]Neis VB, et al. Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice. Pharmacol Biochem Behav. 2015 Mar;130:9-14.

CAS Number: 2482-00-0

Molecular Weight: 228.27

Research Area: Neurological Disease; Cancer

Target: Endogenous Metabolite;Imidazoline Receptor;NO Synthase;Reference Standards
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Artikelnummer MEXHY-101238R-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-101238R-0
Verpackungseinheit Get quote
Mengeneinheit STK
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