Target Synonym: Retinal Dehydrogenase;Aldehyde Dehydrogenase Family 1 Member A;ALDH1A;ALDH-E;HEL;ALDH1A1;ALDC;ALDH-E1;ALDH1;ALDH11;HEL-9;HEL-S-53e;HEL12;PUMB1;RALDH1;Aldehyde Dehydrogenase Cytosolic;Aldehyde Dehydrogenase Family 1 Member A1;ALHDII;PUMB10;RALDH 1;Retinal Dehydrogenase 1
Background: The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.
Immunogen: Recombinant Human ALDH1 protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:2000;FCM 1:25-1:100;ICC/IF 1:20-1:100;
Calculated MW: 55 kDa
Observed MW: 55 kDa
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