Application Note: WB: 1:300-1:5000. ICC/IF: 1:50-200. IHC-P: 1:200-1:400. IHC-Fr: 1:50-200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 28
Form: Liquid
Buffer (with preservative): 10mM TBS, 1% BSA, 50% Glycerol, 0.02% Proclin300.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
Uniprot ID: P15514/Q5U026
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide derived from human Amphiregulin (185-252 aa).
Purification: Purified by Protein A
Conjugation: Unconjugated
Full Name: amphiregulin
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