Anti-Desmoglein 2/DSG2 Antibody Picoband™ (monoclonal, 2B4D1)

Clone Number: 2B4D1

Immunogen: E.coli-derived human Desmoglein 2/DSG2 recombinant protein (Position: L24-E1020).

Concentration: Adding 0.2 ml of distilled water =f 500 μg/ml.

Format: Lyophilized

Storage buffer: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Additional info: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. Background: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance. Subcellular Localization: Tissue Specificity:

• Artikelnummer: SANMON23909
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23909
• Verpackungseinheit: 100μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Western Blotting, Immunohistochemistry
• Isotyp: IgG1
• Wirt: Mouse