Anti-erbB-2 (Her-2/neu) (4D5-8 (trastuzumab)), Human IgG1, CONJUmAb™, kappa

CloneID: 4D5-8 (trastuzumab)

Heavy Chain modification: CONJUmAb™

Antigen Long Description: A431 cells (human epidermoid carcinoma) (over)expressing EGFR.

Buffer Composition: PBS only

Uniprot Accession No.: P04626

Specificity Statement: Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.

Application Notes (Clone): This antibody binds to erbB-2/Her-2/neu has therapeutic indications particularly in the treatment of breast cancer (c.f. Herceptin). It can also be used to detect HER-2 by flow cytometry or IHC (Glazyrin 2007).

• Artikelnummer: ABAAb00103-10.0CM-CMV
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00103-10.0CM-CMV
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA, Flow Cytometry, Immunohistochemistry
• Isotyp: IgG1 kappa
• Wirt: Human