Anti-HTT (iVHH4)

Anti-HTT [iVHH4], Recombinant, VHH, Camelid

CloneID: iVHH4

Heavy Chain modification: His-tagged

Antigen Long Description: The original antibody was generated by immunizing a llama with N-terminal htt protein, followed by phage-VHH display library construction. The antibody was isolated by biopanning against wild-type or mutant N-terminal htt fragment.

Buffer Composition: PBS only.

Uniprot Accession No.: P42858

Specificity Statement: The antibody is specific for wild-type and mutant human huntingtin under native and denatured conditions. The antibody epitope is located between amino acids 49–148.

Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody detected the htt by western blot analysis. The antibody could co-immunoprecipitate htt from human HD brain lysates (Schut et al., 2015; PMID: 25294428).

• Artikelnummer: ABAAb04673-34.11-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04673-34.11-BT
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunoprecipitation, Western Blotting, ELISA
• Isotyp: VHH
• Wirt: Camelid