AP-4-139B, CAS 2716909-84-9

AP-4-139B, CAS 2716909-84-9
Artikelnummer
MEXHY-162567-25
Verpackungseinheit
25 mg
Hersteller
MedChemExpress

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Product Description: AP-4-139B is a heat shock protein 70 inhibitor (IC50=180 nM). HSP70 is a protein that is overexpressed in many types of cancer and is closely related to the survival and proliferation of tumor cells. AP-4-139B exhibits significant cytotoxicity to tumor cells, particularly in colorectal cancer cells. AP-4-139B can be used for cancer research[1][2].

Formula: C34H33BrN3PS

References: [1]Barnoud T, et al. A novel inhibitor of HSP70 induces mitochondrial toxicity and immune cell recruitment in tumors[J]. Cancer research, 2020, 80(23): 5270-5281./[2]Ferretti G D S, et al. HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer[J]. Cell Death & Differentiation, 2024: 1-16.

CAS Number: 2716909-84-9

Molecular Weight: 626.59

Compound Purity: 98.87

Research Area: Cancer

Target: HSP
Mehr Informationen
Artikelnummer MEXHY-162567-25
Hersteller MedChemExpress
Hersteller Artikelnummer HY-162567-25
Verpackungseinheit 25 mg
Mengeneinheit STK
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