APC 366, CAS 158921-85-8

Product Description: APC 366 is a selective inhibitor of mast cell tryptase (Ki=7.1 μM). APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep model of allergic asthma[1][2].

Applications: COVID-19-immunoregulation

Formula: C22H28N6O4

References: [1]Barrios VE, et al. Tryptase mediates hyperresponsiveness in isolated guinea pig bronchi. Life Sci. 1998;63(26):2295-2303. /[2]Krishna MT, et al. Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma. J Allergy Clin Immunol. 2001;107(6):1039-1045.

CAS Number: 158921-85-8

Molecular Weight: 440.50

Compound Purity: 99.81

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Ser/Thr Protease

• Artikelnummer: MEXHY-105999-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-105999-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK