Description: ARF(26–44), cell-permeable is an anti-tumor peptide derived from a specific amino acid sequence of the p14ARF tumor suppressor protein. It serves as an inhibitor of FoxM1, a forkhead box M1 transcription factor, and has demonstrated significant anti-tumor activity in the treatment of mouse hepatocellular carcinoma (HCC). This activity includes increasing apoptosis and reducing tumor cell proliferation and angiogenesis. ARF(26–44), cell-permeable is useful for research in cancer therapy.
CAS Number: 935732-44-8
Formula: C149H267N69O33S
Molecular Weight: 3585,22