AZ 11645373, CAS 227088-94-0

Product Description: AZ11645373 is a highly selective and potent antagonist at human but not rat P2X7 receptors，AZ11645373 inhibits ATP-evoked IL-1β release from lipopolysaccharide-activated THP-1 cells , with an IC50 value of 90 nM[1].

Applications: COVID-19-immunoregulation

Formula: C24H21N3O5S

References: [1]Stokes L, et al. Characterization of a selective and potent antagonist of human P2X(7) receptors, AZ11645373. Br J Pharmacol. 2006 Dec;149(7):880-7.

CAS Number: 227088-94-0

Molecular Weight: 463.51

Compound Purity: 99.54

Research Area: Inflammation/Immunology

Solubility: DMSO : 17.5 mg/mL (ultrasonic;warming;heat to 60°C)

Target: P2X Receptor

• Artikelnummer: MEXHY-108670-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-108670-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK