Target: BDNF
Conjugate: Unconjugated
Product Type: Polyclonal
Immunogen: Synthetic peptide from the N-terminal of human BDNF
Swiss-Prot: P23560
Purification: Peptide Affinity Purified
Storage Buffer: PBS, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated
Concentration: 1 mg/ml
Specificity: Predicted molecular weight at ~27.9kDa.
Cellular Localization: Secreted
Scientific Background: Brain-derived neurotrophic factor, also known as BDNF, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical Nerve Growth Factor. Neurotrophic factors are found in the brain and the periphery. The effects of BDNF on motor neurons might be useful in treating patients with motor neuropathies and ALS (1-3).
References: 1. Wetmore C., Ernfors P., Persson H., Olson L. (1990) Exp. Neurol. 109(2): 141-152.2. Thoenen H., Zafra F., Hengerer B., Lindholm D. (1991) Ann NY Acad Sci. 640: 86-90.3. Chun H.S., Son J.J., Son J.H. (2000) Neuroreport. 11(3): 511-514.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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