Clone Name: HL3678
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody is specific for human ADRB1 protein and does not cross react with human ADRA1A, ADRA1B, ADRA1D, ADRA2A, and ADRB2 protein.<br>This antibody was raised against human beta 1 Adrenergic Receptor Intracellular domain.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]
Uniprot ID: P08588
Antigen Species: Human
Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human beta 1 Adrenergic Receptor. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: adrenoceptor beta 1
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