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Biotinylated CCL14 Protein
Biotinylated CCL14 Protein
Artikelnummer
AVIOPCB00022-5UG
Verpackungseinheit
5µg
Hersteller
Aviva Systems Biology
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Conjugation: Biotin
Description of Target: Hemofiltrate CC chemokine-1(HCC-1)(CCL14) is constitutively expressed by numerous tissues. Upon processing of the N terminal residues of the full length HCC-1 by the uPA-plasmin system, the active form of HCC-1 is a strong agonist for CCR1, CCR5 and to a lesser extent CCR3, and causes chemotaxis of different types of leukocytes. The active form of HCC-1 is also shown as a potent inhibitor of HIV entry.
Key Reference: 1. "HCC-1, a novel chemokine from human plasma"
Schulz-Knappe P., Mägert H., Dewald B., etc
J Exp Med 183:295-299 (1996)
2. "Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [9–74] Processed Variant"
Vakili J., Standker L., Detheux M., Vassart, G., Forssmann W., Parmentier M
J Immunol 167:3406-3413 (2001)
Product Format: Lyophilized
Purity: > 97% as determined by SDS-PAGE
Source: E. coli
Description of Target: Hemofiltrate CC chemokine-1(HCC-1)(CCL14) is constitutively expressed by numerous tissues. Upon processing of the N terminal residues of the full length HCC-1 by the uPA-plasmin system, the active form of HCC-1 is a strong agonist for CCR1, CCR5 and to a lesser extent CCR3, and causes chemotaxis of different types of leukocytes. The active form of HCC-1 is also shown as a potent inhibitor of HIV entry.
Key Reference: 1. "HCC-1, a novel chemokine from human plasma"
Schulz-Knappe P., Mägert H., Dewald B., etc
J Exp Med 183:295-299 (1996)
2. "Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [9–74] Processed Variant"
Vakili J., Standker L., Detheux M., Vassart, G., Forssmann W., Parmentier M
J Immunol 167:3406-3413 (2001)
Product Format: Lyophilized
Purity: > 97% as determined by SDS-PAGE
Source: E. coli
| Artikelnummer | AVIOPCB00022-5UG |
|---|---|
| Hersteller | Aviva Systems Biology |
| Hersteller Artikelnummer | OPCB00022-5UG |
| Green Labware | Nein |
| Verpackungseinheit | 5µg |
| Mengeneinheit | STK |
| Methode | Cell Assay |
| Human Gene ID | 6358 |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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Gernot Ensinger, M.Sc.
