Biotinylated CCL28 Protein

Conjugation: Biotin

Description of Target: Mucosae-associated epithelial chemokine (MEC)(CCL28) is secreted by epithelial cells of gastrointestinal and nonintestinal mucosal cells, and regulates chemotaxis of cells expressing surface receptors CCR3 and CCR10. It shows broad-spectrum antibacterial activities, and could also be useful in vaccination of HIV infeaction.

Key Reference: 1. "A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues"
Pan et al.
J. Immunol. 165: 2943–2949 (2000)

2. Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2).
Wang et al.
J. Biol. Chem. 275: 22313–22323 (2000)

3. "The Mucosae-Associated Epithelial Chemokine (MEC/CCL28) Modulates Immunity in HIV Infection"
Castelletti E. at al.
PLoS ONE 2:e969 (2007)

Product Format: Lyophilized

Purity: > 97% as determined by SDS-PAGE

Source: E. coli

• Artikelnummer: AVIOPCB00019-5UG
• Hersteller: Aviva Systems Biology
• Hersteller Artikelnummer: OPCB00019-5UG
• Verpackungseinheit: 5µg
• Mengeneinheit: STK
• Methode: Cell-based Assay
• Human Gene ID: 56477