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Biotinylated CCL3 Protein
Biotinylated CCL3 Protein
Artikelnummer
AVIOPCB00018-5UG
Verpackungseinheit
5µg
Hersteller
Aviva Systems Biology
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Conjugation: Biotin
Description of Target: Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
Key Reference: 1. "Macrophage inflammatory protein-1"
Menten P., Wuyts A., Van Damme J.
Cytokine Growth Factor Rev. 13:455-481(2002)
2. "Identification of RANTES, MIP-1, and MIP-1[1] as the major HIV-suppressive factors produced by CD8+T cells"
Cocci F., De Vico A.L., Garzino-Demo A., Arya S.K., Gallo R.C., Lusso P.
Science 270:1811-1815 (1995)
3. "Identification and characterization of an inhibitor of haemopoietic stem cell proliferation"
Graham G.J., Wright E.G., Hewick R., Wolpe S.D., Wilkie N.M., Donaldson D., Lorimore S., Pragnell I.B.
Nature 344:442-444 (1990)
4. "Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors"
Zipfel P.F., Balke J., Irving S.G., Kelly K., Siebenlist U.
J Immunol 142:1582-1590 (1989)
Molecular Weight: 10 kDa
Product Format: Lyophilized
Purity: > 97% as determined by SDS-PAGE
Source: E. coli
Description of Target: Macrophage inflammatory proteins 1-alpha (MIP1alpha)(CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.
Key Reference: 1. "Macrophage inflammatory protein-1"
Menten P., Wuyts A., Van Damme J.
Cytokine Growth Factor Rev. 13:455-481(2002)
2. "Identification of RANTES, MIP-1, and MIP-1[1] as the major HIV-suppressive factors produced by CD8+T cells"
Cocci F., De Vico A.L., Garzino-Demo A., Arya S.K., Gallo R.C., Lusso P.
Science 270:1811-1815 (1995)
3. "Identification and characterization of an inhibitor of haemopoietic stem cell proliferation"
Graham G.J., Wright E.G., Hewick R., Wolpe S.D., Wilkie N.M., Donaldson D., Lorimore S., Pragnell I.B.
Nature 344:442-444 (1990)
4. "Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors"
Zipfel P.F., Balke J., Irving S.G., Kelly K., Siebenlist U.
J Immunol 142:1582-1590 (1989)
Molecular Weight: 10 kDa
Product Format: Lyophilized
Purity: > 97% as determined by SDS-PAGE
Source: E. coli
| Artikelnummer | AVIOPCB00018-5UG |
|---|---|
| Hersteller | Aviva Systems Biology |
| Hersteller Artikelnummer | OPCB00018-5UG |
| Green Labware | Nein |
| Verpackungseinheit | 5µg |
| Mengeneinheit | STK |
| Methode | Cell Assay |
| Human Gene ID | 6348 |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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Gernot Ensinger, M.Sc.
