Product Description: BpV(pic) potassium hydrate is a PTEN inhibitor with IC50 31 nM. BpV(pic) potassium hydrate is also an insulin simulator that activates insulin receptor kinase in cultured liver cancer cells, stimulates adipogenesis in adipocytes, and inhibits the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors in rat hepatosomes[1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C6H8K2NO9V3 2-
References: [1]Schmid AC,et al. Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Lett. 2004 May 21;566(1-3):35-8./[2]Posner BI, et al. Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics. J Biol Chem. 1994 Feb 11;269(6):4596-604.
CAS Number: 148556-27-8
Molecular Weight: 469.15
Compound Purity: 98.8
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: PTEN
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