CEP-9722, CAS 916574-83-9

Product Description: CEP-9722, the proagent of CEP-8983, is a selective and orally active PARP-1 and PARP-2 inhibitor with IC50s of 20 nM and 6 nM, respectively. CEP-9722 has anticancer effects[1][2].

Applications: Cancer-programmed cell death

Formula: C24H26N4O3

References: [1]Weiguo Jian, et al. Activity of CEP-9722, a poly (ADP-ribose) polymerase inhibitor, in urothelial carcinoma correlates inversely with homologous recombination repair response to DNA damage. Anticancer Drugs. 2014 Sep;25(8):878-86./[2]Ruth Plummer, et al. Phase 1 dose-escalation study of the PARP inhibitor CEP-9722 as monotherapy or in combination with temozolomide in patients with solid tumors. Cancer Chemother Pharmacol. 2014 Aug;74(2):257-65.

CAS Number: 916574-83-9

Molecular Weight: 418.49

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PARP

• Artikelnummer: MEXHY-105303-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-105303-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK