Product Description: Chavicol (p-Hydroxyallylbenzene, compound 6) can inhibit acetylcholinesterase (Cholinesterase (ChE)), with an IC50 of 7.42 μM. Chavicol has anti-cancer activity and can suppress the growth, survival, migration, and invasion of cancer cells. Chavicol cytotoxic effect is significant, approximately 31 μg/mL in A-549 cells[1][2].
Applications: Cancer-programmed cell death
Formula: C9H10O
References: [1]Haixiao Lu, et al. Tzumin A and B, two new lignan derivatives from the barks of Sassafras tzumu. Nat Prod Res. 2017 Apr;31(7):829-834./[2]Chellasamy Panneerselvam, et al. Anticancer activity of bioactive compound chavicol as potential toxic against human lung cancer A549 cells. Journal of Drug Delivery Science and Technology. Volume 73, July 2022, 103442.
CAS Number: 501-92-8
Molecular Weight: 134.18
Compound Purity: 97.41
Research Area: Cancer
Target: Cholinesterase (ChE)