Product Description: Chenodeoxycholic acid 3-glucuronide is a metabolite of Chenodeoxycholic acid that can activate the key nuclear receptor (FXR), with an EC50 of 8 μM, and in HEK293T cells, the EC50 for activating FXR is 11 μM[1].
Formula: C30H48O10
References: [1]Serena Mostarda, et al. Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification. Eur J Med Chem. 2018 Jan 20:144:349-358.
CAS Number: 58814-71-4
Molecular Weight: 568.70
Research Area: Metabolic Disease
Target: FXR