Product Description: CHF 4227 free base is an orally active and selective estrogen receptor modulator (SERM) with high affinity to the human estrogen receptor-α and -β (Ki values of 0.017 nM and 0.099 nM, respectively)[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C30H33NO4
References: [1]Elisabetta Galbiati, et al. Pharmacological actions of a novel, potent, tissue-selective benzopyran estrogen. J Pharmacol Exp Ther. 2002 Oct;303(1):196-203. /[2]Maurizio Civelli, et al. Single and multiple ascending dose studies of a novel tissue-selective oestrogen receptor modulator, CHF 4227, in healthy postmenopausal women. Br J Clin Pharmacol. 2007 Sep;64(3):304-16.
CAS Number: 444643-64-5
Molecular Weight: 471.59
Research Area: Endocrinology
Target: Estrogen Receptor/ERR