Product Description: Concanamycin B is a macrolide antibiotic, which can inhibit the cavitation type H+-ATPases, and the IC50 value is 5 nM[1].
Applications: COVID-19-immunoregulation
Formula: C44H71NO14
References: [1]Yilla M, et al. Involvement of the vacuolar H(+)-ATPases in the secretory pathway of HepG2 cells. J Biol Chem. 1993 Sep 5;268(25):19092-100. PMID: 8395529./[2]Woo JT, et al. Inhibition of the acidification of endosomes and lysosomes by the antibiotic concanamycin B in macrophage J774. Eur J Biochem. 1992 Jul 1;207(1):383-9.
CAS Number: 81552-33-2
Molecular Weight: 838.03
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Antibiotic;Proton Pump