CX614, CAS 191744-13-5

Product Description: CX614 is a positive variant modulator of AMPA receptors that enhances excitatory postsynaptic potentials (amplitude and duration) by blocking and slowing the inactivation of responses to glutamate and automatically evokes excitatory postsynaptic currents in neuronal cultures. CX614 can be used in the study of psychiatric disorders such as depression[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C13H13NO4

References: [1]Wei Dai, et al. The Impact and Mechanism of a Novel Allosteric AMPA Receptor Modulator LCX001 on Protection Against Respiratory Depression in Rodents. Front Pharmacol. 2019 Feb 19;10:105./[2]Eleni Dicou, et al. Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain. Brain Res. 2003 Apr 25;970(1-2):221-5.

CAS Number: 191744-13-5

Molecular Weight: 247.25

Compound Purity: 99.94

Research Area: Neurological Disease

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: iGluR

• Artikelnummer: MEXHY-110175-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-110175-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK