Product Description: D-Alanine (Standard) is the analytical standard of D-Alanine. This product is intended for research and analytical applications. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR[1][2].
Formula: C3H7NO2
References: [1]Schmieden V, et al. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol Pharmacol. 1995 Nov;48(5):919-27./[2]Saitoh T, et al. A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br J Pharmacol. 1994 Sep;113(1):165-70./[3]Mao Horio, et al. Effects of D-Amino Acid Oxidase Inhibitor on the Extracellular D-Alanine Levels and the Efficacy of D-Alanine on Dizocilpine-Induced Prepulse Inhibition Deficits in Mice. The Open Clinical Chemistry Journal, 2009, 2: 16-21
CAS Number: 338-69-2
Molecular Weight: 89.09
Research Area: Neurological Disease
Target: Endogenous Metabolite;Reference Standards