DR5/TRAIL R2 Monoclonal Antibody

Target Synonym: UNQ;PRO;Death Receptor;TRAIL Receptor;TNF-Related Apoptosis-Inducing Ligand Receptor;TRICK;ZTNFR;TRAILR;TRAIL-R;KILLER/DR;CD262;DR5;KILLER;KILLER/DR5;TRAIL-R2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9;TNFRSF10B;Death Receptor 5;TNF-Related Apoptosis-Inducing Ligand Receptor 2;TRAIL Receptor 2;Tumor Necrosis Factor Receptor Superfamily Member 10B;UNQ160;PRO186;DR5;KILLER;TNFRSF10b

Background: DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.

Immunogen: Recombinant Human DR5/TRAIL R2 Protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: ICC/IF 1:20-1:100;

• Artikelnummer: ELSAN200049P-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: AN200049P-100
• Verpackungseinheit: 100μL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunocytochemistry
• Isotyp: IgG1
• Wirt: Mouse
• Konjugat: Unconjugated