Product Description: Elarofiban (RWJ-53308) is a nonpeptide, orally active antagonist for fibrinogen receptor αIIbβ3 (GPIIb/IIIa), with an IC50 of 0.15 nM. Elarofiban has the potential for platelet mediated thrombotic disorders research[1].
Applications: Neuroscience-Neuromodulation
Formula: C22H32N4O4
References: [1]Judith H. Cohen, et al. A Practical Synthesis of the Platelet Fibrinogen Antagonist, Elarofiban. Organic Process Research & Development 2003, 7, 866-872./[2]De Corte BL, et al., Piperidine-containing beta-arylpropionic acids as potent antagonists of alphavbeta3/alphavbeta5 integrins. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5227-32.
CAS Number: 198958-88-2
Molecular Weight: 416.51
Research Area: Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Integrin