Product Description: Eritoran tetrasodium (E5564) is a Toll-like receptor 4 (TLR4) antagonist. Eritoran tetrasodium protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran tetrasodium decreases the level of granulocytosis, may alleviate the severity of the "cytokine storm". Eritoran tetrasodium inhibits pathogenesis of filovirus infection. Eritoran tetrasodium has anti-inflammatory activity[1][2].
Applications: COVID-19-anti-virus
Formula: C66H122N2Na4O19P2
References: [1]Younan P, et al. The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge. mBio. 2017 Apr 25;8(2):e00226-17/[2]Sun Y, et al. Inhibition of corneal inflammation by the TLR4 antagonist Eritoran tetrasodium (E5564). Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1247-54.
CAS Number: 185954-98-7
Molecular Weight: 1401.58
Research Area: Infection; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: EBV;Toll-like Receptor (TLR)
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