FABP1 (rat recombinant)

Formulation: A solution in 50 mM of sodium phosphate, pH 7.2, with 20% glycerol and 100 mM sodium chloride

Purity: ≥90%

Shelf life (days): 365

Notes: Fatty acid binding protein 1 (FABP1) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids.{11979} FABP1 is composed of ten antiparallel β strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acids. Expression of FABP1 is decreased in hepatoblastoma and hepatocellular carcinoma making the protein a potential tumor marker. Moreover, studies have suggested FABP1 as a potential biomarker for both liver and kidney injury.{11979} Cayman’s FABP1 has been functionally characterized by a fluorescence displacement assay using the fluorescent fatty acid analogue 11-(dansyl amino)undecanoic acid (DAUDA). Both arachidonic acid and oleic acid effectively displace DAUDA from the FABP binding pocket in a concentration-dependent manner.

• Artikelnummer: CAY10005200-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10005200-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK