FG 7142 (Standard), CAS 78538-74-6

Product Description: FG 7142 (Standard) is the analytical standard of FG 7142. This product is intended for research and analytical applications. FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of?β-adrenoceptors in mouse cerebral cortex[1].

Formula: C13H11N3O

References: [1]Cottone P, et al. FG 7142 specifically reduces meal size and the rate and regularity of sustained feeding in female rats: evidence that benzodiazepine inverse agonists reduce food palatability.Neuropsychopharmacology. 2007 May;32(5):1069-81. Epub 2006 Nov 1.

CAS Number: 78538-74-6

Molecular Weight: 225.25

Research Area: Neurological Disease

Target: GABA Receptor;Reference Standards

• Artikelnummer: MEXHY-100991R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-100991R-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK