Product Description: G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a Ki of 11 nM.
Applications: Cancer-programmed cell death
Formula: C21H18BrNO3
References: [1]Cheng Q, et al. G-1 exerts neuroprotective effects through G protein-coupled estrogen receptor 1 following spinal cord injury in mice. Biosci Rep. 2016 Aug 31;36(4). pii: e00373./[2]Kurt AH, et al. Oxidative/antioxidative enzyme-mediated antiproliferative and proapoptotic effects of the GPER1 agonist G-1 on lung cancer cells. Oncol Lett. 2015 Nov;10(5):3177-3182./[3]Chimento A, et al. GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo. Oncotarget. 2015 Aug 7;6(22):19190-203.
CAS Number: 881639-98-1
Molecular Weight: 412.28
Compound Purity: 99.76
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Estrogen Receptor/ERR
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