Product Description: GI 181771 is a cholecystokinin 1 receptor agonist investigated for the treatment of obesity.
Applications: Metabolism-protein/nucleotide metabolism
Formula: C34H31N5O6
References: [1]Myer JR, et al. Species- and dose-specific pancreatic responses and progression in single- and repeat-dose studies with GI181771X: a novel cholecystokinin 1 receptor agonist in mice, rats, and monkeys. Toxicol Pathol. 2014 Jan;42(1):260-74./[2]Roses AD, et al. Stimulation of cholecystokinin-A receptors with Gl181771X: a failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake. Clin Pharmacol Ther. 2009 Apr;85(4):362-5.
CAS Number: 305366-98-7
Molecular Weight: 605.64
Research Area: Metabolic Disease; Endocrinology
Solubility: 10 mM in DMSO
Target: Cholecystokinin Receptor