GNB3 antibody, Internal

GNB3 antibody, Internal
Artikelnummer
GTX89343-100
Verpackungseinheit
100 μg
Hersteller
GeneTex

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Application Note: WB: 1-3μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 37

Positive Control: The peptide used to generate this antibody is available for purchase (GTX89343-PEP).

Specificity/Sensitivity: No cross-reactivity expected with GNB1, 2 and 4

Form: Liquid

Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.

Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]

Uniprot ID: P16520

Antigen Species: Human

Immunogen: Peptide with sequence DCMSLAVSPDFN, from the internal region of the protein sequence according to NP_002066.1.

Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation: Unconjugated

Full Name: G protein subunit beta 3
Mehr Informationen
Artikelnummer GTX89343-100
Hersteller GeneTex
Hersteller Artikelnummer GTX89343-100
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Human
Klonalität Polyclonal
Methode Western Blotting
Isotyp IgG
Human Gene ID 2784
Wirt Goat
Konjugat Unconjugated
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