GR127935 (hydrochloride), CAS 148642-42-6

GR127935 (hydrochloride), CAS 148642-42-6
Artikelnummer
MEXHY-100794-10
Verpackungseinheit
10 mg
Hersteller
MedChemExpress

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Product Description: GR127935 hydrochloride is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 hydrochloride can be used in neurological disease research[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C29H32ClN5O3

References: [1]J W Clitherow, et al. Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists. J Med Chem. 1994 Jul 22;37(15):2253-7./[2]Mohammad Nasehi, et al. Possible involvement of CA1 5-HT1B/1D and 5-HT2A/2B/2C receptors in harmaline-induced amnesia. Pharmacol Biochem Behav. 2014 Oct;125:70-77.

CAS Number: 148642-42-6

Molecular Weight: 534.05

Compound Purity: 99.38

Research Area: Neurological Disease

Solubility: DMSO : 83.33 mg/mL (ultrasonic)

Target: 5-HT Receptor
Mehr Informationen
Artikelnummer MEXHY-100794-10
Hersteller MedChemExpress
Hersteller Artikelnummer HY-100794-10
Verpackungseinheit 10 mg
Mengeneinheit STK
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