Product Description: GSK256066 (Standard) is the analytical standard of GSK256066. This product is intended for research and analytical applications. GSK256066 is a selective and high-affinity phosphodiesterase 4 (PDE4) inhibitor, with an IC50 of 3.2 pM for PDE4B. GSK256066 is developed for the research of chronic obstructive pulmonary disease[1].
Formula: C27H26N4O5S
References: [1]Tralau-Stewart CJ, et al. GSK256066, an exceptionally high-affinity and selective inhibitor of phosphodiesterase 4 suitable for administration by inhalation: in vitro, kinetic, and in vivo characterization. J Pharmacol Exp Ther, 2011, 337(1), 145-154./[2]Nials AT, et al. In vivo characterization of GSK256066, a high-affinity inhaled phosphodiesterase 4 inhibitor. J Pharmacol Exp Ther, 2011, 337(1), 137-144.
CAS Number: 801312-28-7
Molecular Weight: 518.58
Research Area: Inflammation/Immunology
Target: Phosphodiesterase (PDE);Reference Standards
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