Clone Name: HMV314
Light Chain: Lambda
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Form: Liquid
Buffer (with preservative): PBS, 2% BSA, 0.025% ProClin 300.
Concentration: 0.44 mg/ml
Background: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Uniprot ID: P52926
Antigen Species: Human
Immunogen: Recombinant fragment of human HMGA2
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: high mobility group AT-hook 2
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