Background: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. [provided by RefSeq, Jul 2008]
Description: Recombinant human CSPG4(1538-2221) Protein with C-terminal human Fc tag
Molecular Weight: The protein has a predicted molecular mass of 98.9 kDa after removal of the signal peptide. The apparent molecular mass of CSPG4(1538-2221)-hFc is approximately 100-250 kDa due to glycosylation.
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Tag: C-Human Fc tag
Expression Host: HEK293
Formulation & Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Target: CSPG4
Uniprot ID: Q6UVK1
Usage: Research use only
Molecular Characterization: CSPG4(Gln1538-Asn2221) hFc(Glu99-Ala330)
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
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