Human LOX-1 Protein, hFc Tag

Human LOX-1 Protein, hFc Tag
Artikelnummer
DMAPME101312-50
Verpackungseinheit
50 µg
Hersteller
DIMA Biotechnology

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Background: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Description: Recombinant Human LOX-1 Protein with N-terminal human Fc tag

Molecular Weight: The protein has a predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of hFc-LOX-1 is approximately 55-70 kDa due to glycosylation.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Tag: N-Human Fc Tag

Expression Host: HEK293

Formulation & Reconstitution: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Target: LOX-1

Uniprot ID: P78380

Usage: Research use only

Molecular Characterization: hFc(Glu99-Ala330) LOX-1(Met58-Gln273)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Mehr Informationen
Artikelnummer DMAPME101312-50
Hersteller DIMA Biotechnology
Hersteller Artikelnummer PME101312-50
Verpackungseinheit 50 µg
Mengeneinheit STK
Konjugat Unconjugated
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MSDS (PDF) Download