Background: This protein belongs to the the transmembrane and coiled-coil domain (TMCC) family, which shares common structural motifs (two transmembrane domains and two coiled-coil domains). TMCC3 was isolated as a novel gene isolated from human brain, and later became known as a novel gene up-regulated in the developing brain, especially in the ventral tegmentum. There is no resolved structure or defined function.
Description: Human TMCC3-Strep full length protein-synthetic nanodisc
Molecular Weight: The human full length TMCC3-Strep protein has a MW of 53.8 kDa
Protein Families: Transmembrane
Protein Pathways: N/A
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Tag: C-Flag&Strep Tag
Expression Host: HEK293
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Target: TMCC3
Uniprot ID: Q9ULS5
Usage: Research use only
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